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Severe fatigue may indicate a dosing adjustment is needed rather than discontinuation

If additional blood glucose control is required, the dose can be increased after 4 weeks to 2 mg once weekly, which is the maximum recommended dose

Temporary breaks are possible with medical guidance, though longer gaps increase the risk of appetite and weight rebound

And if you're noticing signs like persistent dizziness, significantly reduced urination, or ongoing vomiting or diarrhea, that's a conversation for your provider, not something to wait out.

The SURPASS program (type 2 diabetes) enrolled more than 19,000 participants across 10 trials